Jie Chen Selected Research

Silicon Dioxide (Silica)

10/2023	Fibroblast-derived CXCL14 aggravates crystalline silica-induced pulmonary fibrosis by mediating polarization and recruitment of interstitial macrophages.
10/2023	Crystalline Silica-Induced Proinflammatory Interstitial Macrophage Recruitment through Notch3 Signaling Promotes the Pathogenesis of Silicosis.
1/2023	Crystalline silica-induced macrophage pyroptosis interacting with mitophagy contributes to pulmonary fibrosis via modulating mitochondria homeostasis.
1/2023	The aggravate role of exosomal circRNA11:120406118\|12040782 on macrophage pyroptosis through miR-30b-5p/NLRP3 axis in silica-induced lung fibrosis.
1/2023	Macrophage-derived exosomal lncRNA MSTRG.91634.7 inhibits fibroblasts activation by targeting PINK1 in silica-induced lung fibrosis.
9/2022	Oridonin attenuates lung inflammation and fibrosis in silicosis via covalent targeting iNOS.
6/2021	Inhibition of ER stress by targeting the IRE1α-TXNDC5 pathway alleviates crystalline silica-induced pulmonary fibrosis.
1/2020	Nano-Platelets as an Oxygen Regulator for Augmenting Starvation Therapy Against Hypoxic Tumor.
1/2020	Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediated Autophagy-Lysosomal System in Alveolar Macrophages.
1/2019	Dihydrotanshinone I Alleviates Crystalline Silica-Induced Pulmonary Inflammation by Regulation of the Th Immune Response and Inhibition of STAT1/STAT3.

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Jie Chen Research Topics

Disease

830	Neoplasms (Cancer) 05/2024 - 04/2002
174	Inflammation (Inflammations) 04/2024 - 03/2002
171	Infections 04/2024 - 01/2002
171	Neoplasm Metastasis (Metastasis) 02/2024 - 05/2002
152	Hepatocellular Carcinoma (Hepatoma) 05/2024 - 02/2003
112	Breast Neoplasms (Breast Cancer) 04/2024 - 07/2003
89	Fibrosis (Cirrhosis) 02/2024 - 03/2003
88	Carcinogenesis 03/2024 - 04/2002
58	Carcinoma (Carcinomatosis) 07/2023 - 01/2003
58	Stomach Neoplasms (Stomach Cancer) 02/2023 - 01/2003
53	Lung Neoplasms (Lung Cancer) 12/2024 - 04/2002
52	Hypoxia (Hypoxemia) 10/2023 - 04/2008
51	Pain (Aches) 05/2024 - 01/2009
48	Wounds and Injuries (Trauma) 04/2024 - 04/2006
45	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2024 - 01/2004
45	Obesity 03/2024 - 07/2007
42	Hypertension (High Blood Pressure) 02/2024 - 01/2003
42	Colorectal Neoplasms (Colorectal Cancer) 12/2023 - 01/2005
42	Body Weight (Weight, Body) 11/2023 - 01/2005
39	Pneumonia (Pneumonitis) 04/2024 - 12/2008
38	Adenocarcinoma 05/2024 - 02/2002
37	Stroke (Strokes) 05/2024 - 07/2008
37	Pancreatic Neoplasms (Pancreatic Cancer) 01/2023 - 02/2002
35	Liver Neoplasms (Liver Cancer) 01/2023 - 06/2003
33	COVID-19 05/2024 - 01/2020
33	Thrombosis (Thrombus) 01/2024 - 08/2006
32	Prostatic Neoplasms (Prostate Cancer) 02/2024 - 07/2004
32	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2024 - 10/2012
32	Insulin Resistance 04/2023 - 01/2008
31	Ovarian Neoplasms (Ovarian Cancer) 12/2023 - 02/2003
30	Type 2 Diabetes Mellitus (MODY) 04/2024 - 03/2002
30	Silicosis 10/2023 - 02/2004
30	Hemorrhage 09/2023 - 01/2005
29	Liver Cirrhosis (Hepatic Cirrhosis) 02/2024 - 03/2007
27	Non-alcoholic Fatty Liver Disease 02/2024 - 08/2009
26	Disease Progression 02/2024 - 02/2003
26	Necrosis 04/2023 - 07/2006
25	Lymphatic Metastasis 03/2024 - 01/2006
24	Sepsis (Septicemia) 04/2024 - 09/2012
24	Cardiovascular Diseases (Cardiovascular Disease) 01/2024 - 11/2009
24	Leukemia 12/2023 - 06/2003
23	Adenocarcinoma of Lung 04/2024 - 04/2002
23	Alzheimer Disease (Alzheimer's Disease) 01/2024 - 04/2009
22	Hepatitis B 03/2024 - 05/2010
21	Esophageal Squamous Cell Carcinoma 03/2024 - 01/2015
21	Parkinson Disease (Parkinson's Disease) 01/2024 - 02/2011
21	Asthma (Bronchial Asthma) 12/2023 - 08/2009
20	Chronic Obstructive Pulmonary Disease (COPD) 05/2024 - 12/2003
20	Autism Spectrum Disorder 04/2024 - 09/2017
20	Cognitive Dysfunction 02/2024 - 01/2011
20	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2024 - 10/2009

Drug/Important Bio-Agent (IBA)

283	Proteins (Proteins, Gene)FDA Link 04/2024 - 02/2002
191	Biomarkers (Surrogate Marker)IBA 05/2024 - 01/2006
108	Messenger RNA (mRNA)IBA 04/2024 - 04/2002
76	MicroRNAs (MicroRNA)IBA 02/2024 - 12/2008
73	CytokinesIBA 03/2024 - 12/2003
63	Glucose (Dextrose)FDA LinkGeneric 02/2024 - 03/2002
62	EnzymesIBA 04/2024 - 01/2003
61	RNA (Ribonucleic Acid)IBA 12/2023 - 06/2003
60	Long Noncoding RNAIBA 02/2024 - 01/2014
55	DNA (Deoxyribonucleic Acid)IBA 04/2024 - 05/2002
50	LipidsIBA 05/2024 - 03/2012
43	AntigensIBA 03/2024 - 01/2009
40	Small Interfering RNA (siRNA)IBA 02/2024 - 05/2004
39	Therapeutic UsesIBA 04/2024 - 02/2004
34	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2024 - 08/2006
34	LigandsIBA 12/2023 - 06/2005
33	Immune Checkpoint InhibitorsIBA 04/2024 - 01/2019
33	Indicators and Reagents (Reagents)IBA 05/2023 - 06/2003
32	CateninsIBA 04/2024 - 01/2011
31	Transcription Factors (Transcription Factor)IBA 04/2024 - 06/2005
31	Interleukin-6 (Interleukin 6)IBA 02/2024 - 12/2003
31	Cisplatin (Platino)FDA LinkGeneric 01/2024 - 05/2004
31	CollagenIBA 12/2023 - 01/2002
30	Anti-Bacterial Agents (Antibiotics)IBA 05/2024 - 07/2008
30	Silicon Dioxide (Silica)FDA LinkGeneric 10/2023 - 05/2009
29	Peptides (Polypeptides)IBA 04/2024 - 01/2003
29	Phosphotransferases (Kinase)IBA 02/2024 - 09/2005
28	Oxygen (Dioxygen)IBA 05/2024 - 11/2008
27	Antiviral Agents (Antivirals)IBA 03/2024 - 01/2012
26	AntioxidantsIBA 01/2024 - 11/2004
25	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2023 - 01/2006
24	Insulin (Novolin)FDA Link 04/2024 - 03/2002
23	LipopolysaccharidesIBA 02/2024 - 12/2003
22	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2024 - 12/2003
22	ErbB Receptors (EGF Receptor)IBA 01/2024 - 01/2004
20	IronIBA 05/2024 - 12/2011
20	ParaffinIBA 04/2024 - 02/2002
20	Blood Glucose (Blood Sugar)IBA 03/2024 - 10/2016
20	CholesterolIBA 11/2023 - 12/2003
20	Circular RNAIBA 07/2023 - 04/2016
20	IodineIBA 01/2017 - 06/2005

Therapy/Procedure

380	Therapeutics 05/2024 - 01/2002
114	Drug Therapy (Chemotherapy) 03/2024 - 12/2004
70	Immunotherapy 05/2024 - 05/2010
67	Radiotherapy 03/2024 - 01/2005
26	Length of Stay 03/2024 - 10/2011
26	Aftercare (After-Treatment) 01/2024 - 06/2001
20	Chinese Traditional Medicine (Traditional Chinese Medicine) 03/2024 - 06/2005
20	Transplantation 01/2024 - 10/2005